The mother lode of liver transplantation, with particular reference to our new journal

The mother lode of liver transplantation, with particular reference to our new journal.

LIVER TRANSPLANTATION New Approaches in the Use of CycIosporine: With Particular Reference to the Liver

Six weeks ago, Iwatsuki et at2 summarized at a meeting in Pittsburgh the results with our first 1,000 liver recipients in the so-called esA era. Life-survival was compared with that of 170 historical controls in whom treatment was with azathioprine (or cyclophosphamide) and prednisone, usually with antilymphocyte globulin (ALG). The life-survival curve of patients before esA-steroid therapy sho...

Liver transplantation, 1980, with particular reference to cyclosporin-A.

Acute neurological complications after liver transplantation with particular reference to intraoperative cerebral air embolus.

Nine of 48 adult patients who underwent orthotopic liver transplantation developed significant clinical neurological abnormalities recognized shortly after operation. Decrease in consciousness occurred with resultant coma, focal and generalized seizures and the occasional appearance of a state of akinetic mutism. Neuropathological abnormalities consisted of multifocal areas of infarction in cer...

Acquired immunologic tolerance: with particular reference to transplantation.

The first unequivocally successful bone marrow cell transplantation in humans was recorded in 1968 by the University of Minnesota team of Robert A. Good (Gatti et al. Lancet 2: 1366-1369, 1968). This achievement was a direct extension of mouse models of acquired immunologic tolerance that were established 15 years earlier. In contrast, organ (i.e. kidney) transplantation was accomplished precoc...